CD34 Class II Mouse Monoclonal Antibody [Clone ID: QBEND/10]

Specifications

Product Data
Clone Name	QBEND/10
Applications	FC
Recommended Dilution	Flow Cytometry.
Reactivities	Human, Monkey
Host	Mouse
Isotype	IgG1
Clonality	Monoclonal
Immunogen	Human endothelial vesicles. Spleen cells from immunised NZB mice fused with cells of the NSO mouse myeloma cell line.
Specificity	This antibody recognises the CD34 antigen. QBEND/10 specifically recognises a class II epitope.
Formulation	PBS containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer. Label: PE State: Lyophilized purified IgG fraction. Label: R. Phycoerythrin (RPE)
Reconstitution Method	Restore with distilled water
Purification	Affinity chromatography on Protein A
Conjugation	PE
Storage	Prior to and following reconstitution store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Stability	Shelf life: one year from despatch.
Database Link	Entrez Gene 947 Human UniProt ID P28906
Background	CD34 is a single chain transmembrane glycoprotein of 105 - 120kD. Expressed on haemopoietic cells, including bone marrow and blood. It is expressed on the majority of cells in acute lymphoid leukaemia (ALL) as well as cells in acute myelogenous leukaemia (AML). It is also found on capillary endothelial cells. There are three classes of CD34 epitopes defined by differential sensitivity to enzymatic cleavage with glycoprotease from Pasteurella haemolytica and with neuraminidase.
Synonyms	Hematopoietic progenitor cell marker
Reference Data