CD11c (ITGAX) Mouse Monoclonal Antibody [Clone ID: BU15]

CAT#: SM1834PP

CD11c (ITGAX) mouse monoclonal antibody, clone BU15, PerCP


Product Images

Specifications

Product Data
Clone Name BU15
Applications FC
Recommended Dilution Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension.
The content of a vial (1 ml) is sufficient for 100 tests.
Reactivities Human, Monkey
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Dendritic cells of synovial fluid
Specificity This antibody reacts with CD11c (alphaX, p150), a 150 kDa integrin expressed mainly on dendritic cells and tissue macrophages.
Formulation stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide
Label: PerCP
State: Liquid purified Ig fraction
Label: Conjugated with Peridinin-chlorophyll-protein complex (PerCP) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
Conjugation PerCP
Storage Store undiluted at 2-8°C. DO NOT FREEZE! This products is photosensitive and should be protected from light.
Stability Shelf life: one year from despatch.
Background CD11c (p150, alphaX integrin subunit) forms complex with CD18 (beta2 integrin subunit) and is expressed mainly on tissue macrophages and dendritic cells. CD11c binds to complement fragment iC3b, fibrinogen, VCAM-1 and ICAM-2 or e.g. CD90. Like other beta2 integrins, CD11c/CD18 plays roles in cell migration and phagocytosis. Moreover, interaction of CD11c/CD18 with plasminogen regulates plasmin activities, and interaction with heparin counteracts binding of iC3b.
Synonyms ITGAX, Integrin alpha-X, Leu M5
Reference Data

Documents