Réactifs et instruments pour l'immunologie, la biologie cellulaire et la biologie moléculaire.

Anti-DUSP4 antibody (50-130 Internal)

Imprimer

Référence NB-22-4136-200ul

Conditionnement : 200µg

Contactez votre distributeur local :

Téléphone : +1 850 650 7790

Marque : Neo Biotech

Contactez votre distributeur local :

Téléphone : +1 850 650 7790

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using DUSP4 Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from RAW264.7, A549, COS7, and NIH/3T3 cells, using DUSP4 Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of HEPG2-UV cells using MKP-2 Polyclonal Antibody diluted at 1：1000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

General Info

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Mouse/Rat/Monkey
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Dual specificity protein phosphatase 4 (81-130) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:20000 IF 1:50-200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Information

Gene Symbol:	DUSP4
Gene ID:	1846
Uniprot ID:	DUS4_HUMAN
Immunogen Region:	81-130
Specificity:	MKP-2 Polyclonal Antibody detects endogenous levels of MKP-2 protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from human DUSP4. AA range:81-130

Description

Post Translational Modifications	Phosphorylation in the C-terminus by ERK1/2 inhibits proteasomal degradation and stabilizes the protein.
Function	Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.
Protein Name	Dual Specificity Protein Phosphatase 4 Dual Specificity Protein Phosphatase Hvh2 Mitogen-Activated Protein Kinase Phosphatase 2 Map Kinase Phosphatase 2 Mkp-2
Database Links	Reactome: R-HSA-112409 Reactome: R-HSA-202670 Reactome: R-HSA-5675221
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-Dual Specificity Protein Phosphatase 4 antibody Anti-Dual Specificity Protein Phosphatase Hvh2 antibody Anti-Mitogen-Activated Protein Kinase Phosphatase 2 antibody Anti-Map Kinase Phosphatase 2 antibody Anti-Mkp-2 antibody Anti-DUSP4 antibody Anti-MKP2 antibody Anti-VH2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance