General Info
| Host: | Goat |
| Applications: | WB/IHC-F/IHC-P |
| Reactivity: | Human/Rat/Mouse/Monkey/Canine |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Goat polyclonal antibody anti-Adenosine receptor A2a (360aa C-Term) is suitable for use in Western Blot, Immunohistochemistry and Immunohistochemistry research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS, 20% Glycerol and 0.05% Sodium Azide. |
| Purification: | This antibody is epitope-affinity purified from goat antiserum. |
| Concentration: | 3 mg/ml |
| Dilution Range: | WB 1:500-1:2000IHC-F 1:250-1:1000IHC-P 1:250-1:1000 |
| Storage Instruction: | For continuous use, store at 2-8 C for one-two days. For extended storage, store in-20 C freezer. Working dilution samples should be discarded if not used within 12 hours. |
Information
| Gene Symbol: | ADORA2A |
| Gene ID: | 135 |
| Uniprot ID: | AA2AR_HUMAN |
| Immunogen Region: | 360aa C-Term |
| Accession Number: | ENSG00000128271 |
| Specificity: | Detects endogenous levels of ADORA2A in brain by Western blot. |
| Immunogen: | Recombinant peptide derived from within residues 360 aa to the C-terminus of human ADORA2A produced in E. coli. |
| Immunogen Sequence: | YALGLVSGGSAQESQGNTGL PDVELLSHELKGVCPEPPGL DDPLAQDGAGVS |
Description
| Post Translational Modifications | Ubiquitinated. Deubiquitinated by USP4.leading to stabilization and expression at the cell surface. |
| Function | Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. |
| Protein Name | Adenosine Receptor A2a |
| Database Links | Reactome: R-HSA-187024Reactome: R-HSA-417973Reactome: R-HSA-418555Reactome: R-HSA-5683826 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinColocalizes With Gas2l2 At Neuronal Processes |
| Alternative Antibody Names | Anti-Adenosine Receptor A2a antibodyAnti-ADORA2A antibodyAnti-ADORA2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance