General Info
| Host: | Rabbit |
| Applications: | ELISA/IHC/IP/WB |
| Reactivity: | Human/Monkey/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-HAND2 (1-100) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Biotin |
| Isotype: | IgG |
| Purification: | Affinity Purified |
| Concentration: | 0.53-0.63 µg/µl |
| Dilution Range: | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:100 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Information
| Gene Symbol: | Hand2 |
| Gene ID: | 64637 |
| Uniprot ID: | HAND2_RAT |
| Immunogen Region: | 1-100 |
| Immunogen: | Synthetic peptide taken within amino acid region 1-100 on Human HAND2 protein. |
Description
| Function | Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Also plays an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3'. |
| Protein Name | Heart- And Neural Crest Derivatives-Expressed Protein 2Deciduum - Heart - Autonomic Nervous System And Neural Crest Derivatives-Expressed Protein 2Dhand |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Heart- And Neural Crest Derivatives-Expressed Protein 2 antibodyAnti-Deciduum - Heart - Autonomic Nervous System And Neural Crest Derivatives-Expressed Protein 2 antibodyAnti-Dhand antibodyAnti-Hand2 antibodyAnti-Dhand antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance