Anti-PDCD1LG2 antibody (115-165) {FITC}

Référence NB-22-59233-100

Conditionnement : 100µg

Marque : Neo Biotech

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General Info

Host: Rabbit
Applications: ELISA/IHC/IP/WB
Reactivity: Human/Monkey/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PDCD1LG2 (115-165) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: FITC
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.5 µg/µl
Dilution Range: WB: 1:500
ELISA: 1:10, 000
IP: 1:150
IHC: 1:50-1:150
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Information

Gene Symbol: PDCD1LG2
Gene ID: 80380
Uniprot ID: PD1L2_HUMAN
Immunogen Region: 115-165
Immunogen: Synthetic peptide taken within amino acid region 115-165 on human Programmed cell death 1 ligand 2 protein.

Description

Tissue Specificity Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.
Function Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Protein Name Programmed Cell Death 1 Ligand 2
Pd-1 Ligand 2
Pd-L2
Pdcd1 Ligand 2
Programmed Death Ligand 2
Butyrophilin B7-Dc
B7-Dc
Cd Antigen Cd273
Database Links Reactome: R-HSA-389948
Cellular Localisation Isoform 3: Secreted
Isoform 2: Endomembrane System
Single-Pass Type I Membrane Protein
Isoform 1: Cell Membrane
Alternative Antibody Names Anti-Programmed Cell Death 1 Ligand 2 antibody
Anti-Pd-1 Ligand 2 antibody
Anti-Pd-L2 antibody
Anti-Pdcd1 Ligand 2 antibody
Anti-Programmed Death Ligand 2 antibody
Anti-Butyrophilin B7-Dc antibody
Anti-B7-Dc antibody
Anti-Cd Antigen Cd273 antibody
Anti-PDCD1LG2 antibody
Anti-B7DC antibody
Anti-CD273 antibody
Anti-PDCD1L2 antibody
Anti-PDL2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance