General Info
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-SERPINA12 (20-320) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
Gene Symbol: | SERPINA12 |
Gene ID: | 145264 |
Uniprot ID: | SPA12_HUMAN |
Immunogen Region: | 20-320 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human SERPINA12 (NP_776249.1). |
Immunogen Sequence: | LLKPSFSPRNYKALSEVQGW KQRMAAKELARQNMDLGFKL LKKLAFYNPGRNIFLSPLSI STAFSMLCLGAQDSTLDEIK QGFNFRKMPEKDLHEGFHYI IHELTQKTQDLKLSIGNTLF IDQRLQPQRKFLEDAKNFYS AETILTNFQNLEMAQKQIND FISQKTHGKINNLIENIDPG TVMLLANYIFFRARWKHEFD PNVTKEEDFFLEKNSSVKVP MMFRSGIYQVGYDDKLSCT |
Description
Tissue Specificity | Expressed in visceral adipose tissues. |
Post Translational Modifications | Glycosylation slightly decreases affinity for heparin, but otherwise has no significant effect on KLK7 inhibitory activity or thermal stability of the protein. |
Function | Adipokine that modulates insulin action by specifically inhibiting its target protease KLK7 in white adipose tissues. |
Protein Name | Serpin A12Ol-64Visceral Adipose Tissue-Derived Serine Protease InhibitorVaspinVisceral Adipose-Specific Serpin |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Serpin A12 antibodyAnti-Ol-64 antibodyAnti-Visceral Adipose Tissue-Derived Serine Protease Inhibitor antibodyAnti-Vaspin antibodyAnti-Visceral Adipose-Specific Serpin antibodyAnti-SERPINA12 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance