Anti-SYT1 antibody (1-60) {Biotin}

Clonality:	Polyclonal
Conjugation:	Biotin
Isotype:	IgG
Purification:	Affinity Purified
Concentration:	0.64-0.72 µg/µl
Dilution Range:	WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	SYT1
Gene ID:	6857
Uniprot ID:	SYT1_HUMAN
Immunogen Region:	1-60
Immunogen:	Synthetic peptide taken within amino acid region 1-60 on SYT1 protein.

Tissue Specificity	Expressed in melanocytes.
Post Translational Modifications	Glycosylated.
Function	Calcium sensor that participates in triggering neurotransmitter release at the synapse. May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner.these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes.
Protein Name	Synaptotagmin-1 Synaptotagmin I Syti P65
Database Links	Reactome: R-HSA-181429 Reactome: R-HSA-181430 Reactome: R-HSA-210500 Reactome: R-HSA-212676 Reactome: R-HSA-264642 Reactome: R-HSA-5250958 Reactome: R-HSA-5250989 Reactome: R-HSA-6794361 Reactome: R-HSA-8856825 Reactome: R-HSA-8856828 Reactome: R-HSA-888590
Cellular Localisation	Cytoplasmic Vesicle Secretory Vesicle Membrane Single-Pass Membrane Protein Secretory Vesicle Synaptic Vesicle Membrane Chromaffin Granule Membrane Cytoplasm
Alternative Antibody Names	Anti-Synaptotagmin-1 antibody Anti-Synaptotagmin I antibody Anti-Syti antibody Anti-P65 antibody Anti-SYT1 antibody Anti-SVP65 antibody Anti-SYT antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance