APE1 (APEX1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI4D9]
CAT#: TA800336BM
APEX1 mouse monoclonal antibody,clone 4D9, HRP conjugated
Conjugation: Unconjugated Biotin
Product Images
Specifications
| Product Data | |
| Clone Name | OTI4D9 |
| Applications | IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150 |
| Reactivities | Human, Dog, Rat, Monkey, Mouse |
| Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1-242 of human APEX1 (NP_001632) produced in E.coli. |
| Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol. |
| Concentration | 0.5 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | HRP |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 35.4 kDa |
| Gene Name | apurinic/apyrimidinic endodeoxyribonuclease 1 |
| Database Link | |
| Background | Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq, Jul 2008] |
| Synonyms | APE; APE1; APEN; APEX; APX; HAP1; REF1 |
| Reference Data | |
| Protein Families | Druggable Genome, Stem cell - Pluripotency, Transcription Factors |
| Protein Pathways | Base excision repair |
Documents
| Product Manuals |
| FAQs |
|
| SDS |
Resources
| Antibody Resources |
|
Other Versions
| SKU | Description | Size | |
|---|---|---|---|
| CF800336 | Carrier-free (BSA/glycerol-free) APEX1 mouse monoclonal antibody, clone OTI4D9 (formerly 4D9) | 600,00 EUR | |
| TA800336 | APEX1 mouse monoclonal antibody, clone OTI4D9 (formerly 4D9) | 447,00 EUR | |
| TA800336AM | APEX1 mouse monoclonal antibody,clone 4D9, Biotinylated | 509,00 EUR | |
| TA800336S | APEX1 mouse monoclonal antibody, clone OTI4D9 (formerly 4D9) | 200,00 EUR |