CD3 antibody [CD3-12] (FITC)

Référence GTX43629-25ug

Conditionnement : 25ug

Marque : Genetex

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Host

Rat

Clonality

Monoclonal

Clone Name

CD3-12

Isotype

IgG1

Application

FACS

Reactivity

Human, Mouse, Rabbit, Bovine, Cat, Dog, Chicken, Pig, Alpaca, Amazon Parrot, Bullfrog, Cynomolgus monkey, Duck, Great horned owl (Bubo virginianus), Harbour Porpoise, Horse, Koala, Raccoon, Rhesus Monkey, Sea Lion, Spotted Hyena, Xenopus
Package
25 μg
View product citations for antibody GTX43629 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS 1:50-1:100

Note :

FACS
Membrane permeabilization is required for this application.

Not tested in other applications.

Product Note

This antibody raised against a peptide representing an invariant cytoplasmic  sequence  within  the  CD3ε  chain  recognizes  human  CD3ε.

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Protect from light.

Concentration

0.1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide sequence derived from cytoplasmic epitope of CD3 (Glu-Arg-Pro-Pro-Pro-Val-Pro-Asn-Pro-Asp-Tyr-Glu-Pro-Cys) (ERPPPVPNPDYEPC )

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Fluorescein isothiocyanate (FITC)

RRID

AB_11169769

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

T3E Antibody , TCRE Antibody , CD3e molecule, epsilon (CD3-TCR complex) Antibody , CD3E Antibody

Background

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]

Application Reference

Zhang L et al. Mol Cell Probes 2018; 41 : 43-51 Immunopotentiating effect of Inonotus obliquus fermentation products administered at vaccination in chickens.
Sun F et al. PLoS One 2016; 11 (8) : e0160659 Regulation of Nutritional Metabolism in Transition Dairy Cows: Energy Homeostasis and Health in Response to Post-Ruminal Choline and Methionine.
Application : FACS
Reactivity : Bovine

REVIEW

There are currently no reviews for CD3 antibody [CD3-12] (FITC) (GTX43629). Be the first to share your experience with this product.
Application Reference
Zhang L et al. Mol Cell Probes 2018; 41:43-51 Immunopotentiating effect of Inonotus obliquus fermentation products administered at vaccination in chickens.
Sun F et al. PLoS One 2016; 11 (8):e0160659 Regulation of Nutritional Metabolism in Transition Dairy Cows: Energy Homeostasis and Health in Response to Post-Ruminal Choline and Methionine.
Application : FACS
Reactivity : Bovine
SDS
PBS.pdf
Sodium Azide.pdf

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