Specifications

Product Data
Clone Name	HM57
Applications	FC
Recommended Dilution	Flow Cytometry: Use 10 µl of neat antibody to label 1x10e6 cells in 100 µl; Membrane permeabilisation is required for this application.
Reactivities	Bovine, Canine, Chicken, Equine, Guinea Pig, Human, Monkey, Mouse, Porcine, Rabbit, Rat
Host	Mouse
Isotype	IgG1
Clonality	Monoclonal
Immunogen	Synthetic peptide corresponding to 202-216 amino acid sequence of human mb-1
Specificity	This antibody recognises an epitope within the cytoplasmic domain of CD79a. CD79a, also known as mb-1, is a 45kD protein that is expressed by B lymphocytes during differentiation from early pre-B cell stage through to plasma cells.
Formulation	Phosphate buffered saline pH 7.4 containing 0.09% Sodium Azide (NaN3), 1% Bovine Serum Albumin Label: PE State: Lyophilized Ig fraction Label: R. Phycoerythrin (RPE)
Reconstitution Method	Reconstitute with 0.25 ml distilled water
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	PE
Storage	Store undiluted at 2-8°C. DO NOT FREEZE. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Stability	Shelf life: One year from despatch.
Database Link	Entrez Gene 973 Human UniProt ID P11912
Background	The CD79a molecule associates with CD79b (B29) to form a heterodimer that is non-covalently linked to surface immunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79b heterodimers are also necessary for intracellular signalling following antigen-binding to surface immunoglobulin.
Synonyms	IGA, MB1, B-Cell marker
Reference Data