DAB2IP Polyclonal Antibody, FITC Conjugated
Référence bs-5998R-FITC
Conditionnement : 100ul
Marque : Bioss
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DAB2IP Polyclonal Antibody, FITC Conjugated
Applications
Predicted Reactivity
| Overview | |
| Catalog # | bs-5998R-FITC |
| Product Name | DAB2IP Polyclonal Antibody, FITC Conjugated |
| Applications | WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
| Predicted Reactivity | Human, Mouse, Rat, Dog, Cow, Pig, Horse, Guinea Pig |
| Specifications | |
| Conjugation | FITC |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human DAB2IP |
| Immunogen Range | 901-1069/1069 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 153090 |
| Subcellular location | Cytoplasm, Cell membrane |
| Synonyms | AF9Q34; AIP1; ASK interacting protein; DAB2P_HUMAN; ASK interacting protein 1; ASK1 interacting protein 1; DAB2 interacting protein; DAB2 interaction protein; DAB2P; DIP1/2; Disabled homolog 2 interacting protein; DOC 2/DAB2 interactive protein; FLJ39072; KIAA1743; nGAP like protein. |
| Background | DAB2IP is a Ras GTPase-activating protein (GAP) that acts as a tumor suppressor gene and is inactivated by methylation in prostate and breast cancers. It also interacts with MAP3K5 to disrupt the association of MAP3K5 with the inhibitory 14-3-3 complex. |
| Application Dilution | |
| WB | 1:300-5000 |
| IF(IHC-P) | 1:50-200 |
| IF(IHC-F) | 1:50-200 |
| IF(ICC) | 1:50-200 |