Estrogen receptor beta Antibody, PE-Cy3 Conjugated
Référence bs-0116R-PE-Cy3
Conditionnement : 100ul
Marque : Bioss
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Estrogen receptor beta Antibody, PE-Cy3 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-0116R-PE-Cy3 |
| Product Name | Estrogen receptor beta Antibody, PE-Cy3 Conjugated |
| Applications | WB, FCM |
| Reactivity | Human, Mouse, Rat, Sheep |
| Predicted Reactivity | Cow, Pig |
| Specifications | |
| Conjugation | PE-Cy3 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human ER-beta |
| Immunogen Range | 201-300/530 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 2100 |
| Swiss Prot | Q92731 |
| Subcellular location | Nucleus |
| Synonyms | Erb; ESRB; ESTRB; NR3A2; ER-BETA; ESR-BETA; Estrogen receptor beta; Nuclear receptor subfamily 3 group A member 2; ESR2 |
| Background | Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual. |
| Application Dilution | |
| WB | 1:300-5000 |
| FCM | 1:20-100 |