Fos B (FOSB) Mouse Monoclonal Antibody [Clone ID: OTI5D5]

CAT#: CF804193

Carrier-free (BSA/glycerol-free) FOSB mouse monoclonal antibody, clone OTI5D5 (formerly 5D5)

Formulation: Standard Carrier-Free


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Specifications

Product Data
Clone Name OTI5D5
Applications IHC, WB
Recommended Dilution WB 1:2000
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1-255 of human FOSB (NP_006723) produced in E.coli.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name FosB proto-oncogene, AP-1 transcription factor subunit
Background The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms AP-1; G0S3; GOS3; GOSB
Reference Data
Protein Families Druggable Genome, Transcription Factors

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