GAD67 (GAD1) (1-585) Mouse Monoclonal Antibody [Clone ID: 9A6]
CAT#: AM26579AF-N
GAD67 (GAD1) (1-585) mouse monoclonal antibody, clone 9A6, Azide Free
Specifications
Product Data | |
Clone Name | 9A6 |
Applications | IHC, WB |
Recommended Dilution | Western blot: 1 μg/ml for chemiluminescence detection system. Immunohistochemistry on paraffin sections: 1-10 μg/ml. |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Recombinant GST-human brain GAD 65 fusion protein corresponding to full-length amino acids (1-585 a.a.) |
Specificity | This antibody reacts with GAD 65 and GAD 67 on Western blotting and Immunohistochemistry in murine and rat samples. It detects 65 kDa and 67 kDa GAD by Western blotting using mouse and rat total brain cell lysate. |
Formulation | PBS containing 50% glycerol, pH 7.2. Contains no preservatives. State: Azide Free State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Protein A agarose |
Conjugation | Unconjugated |
Storage | Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: One year from despatch. |
Gene Name | glutamate decarboxylase 1 |
Database Link | |
Background | Glutamic acid decarboxylase (GAD) catalyzes formation of γ -Aminobutyric acid (GABA), which is an inhibitory neurotransmitter, and is present in brain as well as several tissues outside the central nervous system. Biological functions of GAD and GABA extend beyond regulation of neurotransmission to include effects on the immune system as well as modulation of cell proliferation, protein synthesis, and metabolism. Two isoforms of GAD, GAD 65 and GAD 67 , each derived from a single separate gene, were isolated from human fetal brain λ gt11 cDNA library. |
Synonyms | Glutamate decarboxylase 1, GAD-67 |
Note | This product was originally produced by MBL International. Protocol: SDS-PAGE & Western Blotting Immunohistochemical staini ng for paraffin- embedded sections: SAB method |
Reference Data |
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