Glimepiride urethane

Référence orb1738196-50mg

Conditionnement : 50mg

Marque : Biorbyt

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    Glimepiride urethane

    Glimepiride urethane

    Catalog Number: orb1738196

    Catalog Numberorb1738196
    CategorySmall Molecules
    DescriptionGlimepiride urethane
    CAS Number119018-30-3
    Purity0.98
    MW409.46
    SMILESC(NCCC1=CC=C(S(NC(OC)=O)(=O)=O)C=C1)(=O)N2C(=O)C(CC)=C(C)C2
    FormulaC18H23N3O6S
    Biological ActivityGlimepiride urethane is a third generation sulfonylurea compound, which increases the release of insulin from pancreatic beta cells. In addition, glimepiride increases the activity of intracellular insulin receptors. Glimepiride increases osteoblast proliferation and differentiation, which is thought to be related to its ability to activate the PI3K and Akt pathway. Furthermore, Glimepiride enhances intrinsic peroxisome proliferator-activated receptor γ activity. Glimepiride also increases protein expression of glucose transports 1 and 4, and is a potent KIR channel blocker.
    NoteFor research use only
    Expiration Date12 months from date of receipt.