Human Adiponectin (ADIPOQ) activation kit by CRISPRa

CAT#: GA106250

ADIPOQ CRISPRa kit - CRISPR gene activation of human adiponectin, C1Q and collagen domain containing



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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol ADIPOQ
Locus ID 9370
Kit Components

GA106250G1, Adiponectin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106250G2, Adiponectin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106250G3, Adiponectin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001177800, NM_004797
UniProt ID Q15848
Synonyms ACDC; ACRP30; ADIPQTL1; ADPN; APM-1; APM1; GBP28
Summary This gene is expressed in adipose tissue exclusively. It encodes a protein with similarity to collagens X and VIII and complement factor C1q. The encoded protein circulates in the plasma and is involved with metabolic and hormonal processes. Mutations in this gene are associated with adiponectin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Apr 2010]

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