Conditionnement : 40assays
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c-Jun N-terminal kinase (JNK) is a member of the mitogen-activated protein (MAP) kinase family identified in mammals. Activation of JNK plays an critical role in neuronal apoptosis and other physiological and pathological processes.
The KinaseSTAR JNK Activity Assay Kit provides a specific and simple way for detection of JNK activity based on Western Blot method. The assay uses a JNK-specific antibody to immunoprecipitate JNK from cell or tissue lysates. The kinase reaction conducted to detect JNK activity is performed using recombinant c-Jun as substrate. The phosphorylation of c-Jun is analyzed by western blot method using a phospho-c-Jun specific antibody. The kit specifically detects JNK, without other kinase activity can be detected.