MEK1 (MAP2K1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI4E1]
CAT#: TA506006BM
MAP2K1 mouse monoclonal antibody,clone 4E1, HRP conjugated
Conjugation: Unconjugated Biotin
Specifications
| Product Data | |
| Clone Name | OTI4E1 |
| Applications | IF, IHC, WB |
| Recommended Dilution | WB 1:200~2000, IHC 1:150, IF 1:100 |
| Reactivities | Human, Dog, Rat, Monkey, Mouse |
| Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human MAP2K1(NP_002746) produced in HEK293T cell. |
| Formulation | PBS (pH 7.4) containing 1% BSA, 50% glycerol. |
| Concentration | 0.5 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | HRP |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 43.3 kDa |
| Gene Name | mitogen-activated protein kinase kinase 1 |
| Database Link | |
| Background | The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul |
| Synonyms | CFC3; MAPKK1; MEK1; MKK1; PRKMK1 |
| Reference Data | |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Acute myeloid leukemia, B cell receptor signaling pathway, Bladder cancer, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Dorso-ventral axis formation, Endometrial cancer, ErbB signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Gap junction, Glioma, GnRH signaling pathway, Insulin signaling pathway, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Oocyte meiosis, Pancreatic cancer, Pathways in cancer, Prion diseases, Progesterone-mediated oocyte maturation, Prostate cancer, Regulation of actin cytoskeleton, Renal cell carcinoma, T cell receptor signaling pathway, Thyroid cancer, Toll-like receptor signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway |
Documents
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| SDS |
Resources
| Antibody Resources |
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Other Versions
| SKU | Description | Size | |
|---|---|---|---|
| CF506006 | Carrier-free (BSA/glycerol-free) MAP2K1 mouse monoclonal antibody,clone OTI4E1 | 600,00 EUR | |
| TA506006 | MAP2K1 mouse monoclonal antibody,clone OTI4E1 | 447,00 EUR | |
| TA506006AM | MAP2K1 mouse monoclonal antibody,clone 4E1, Biotinylated | 509,00 EUR | |
| TA506006S | MAP2K1 mouse monoclonal antibody,clone OTI4E1 | 200,00 EUR |