Réactifs et instruments pour l'immunologie, la biologie cellulaire et la biologie moléculaire.

OTP Polyclonal Antibody, FITC Conjugated

Imprimer

Référence bs-11920R-FITC

Conditionnement : 100ul

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Téléphone : +1 850 650 7790

Marque : Bioss

Contactez votre distributeur local :

Téléphone : +1 850 650 7790

bs-11920R-FITC [Conjugated Primary Antibody]

OTP Polyclonal Antibody, FITC Conjugated

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DATASHEET

Host: Rabbit

Target Protein: OTP

Immunogen Range: 121-220/325

Clonality: Polyclonal

Isotype: IgG

Source: KLH conjugated synthetic peptide derived from human OTP

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Homeodomain (HD) genes are helix-turn-helix transcription factors that play key roles in the specification of cell fates. OTP (orthopedia homeobox) is a 325 amino acid nuclear protein belonging to the paired homeobox family and Bicoid subfamily. OTP is expressed in neurons, which give rise to the paraventricular (PVN), supraoptic (SON), anterior periventricular (aPV) and arcuate (ARN) nuclei. Containing a homeobox DNA-binding domain and a OAR domain, OTP is suggested to be involved in the differentiation of hypothalamic neuroendocrine cells. At early embryonic stages in mice, the expression of SIM2 is downregulated in the absence of OTP, indicating a potential role for OTP as an upstream regulator of SIM2. OTP is highly conserved in evolution and is encoded by a gene located on human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome.

Conjugation: FITC

Excitation/ Emission: 494nm/518nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 34

Predicted Cross Reactive Species: Human
Mouse
Rat
Dog
Cow
Sheep
Pig
Horse
Chicken
Rabbit
Drosophila

For research use only. Not intended for diagnostic or therapeutic use.