Réactifs et instruments pour l'immunologie, la biologie cellulaire et la biologie moléculaire.

PIK3R1(Tyr556) Polyclonal Antibody, HRP Conjugated

Imprimer

Référence bs-5572R-HRP

Conditionnement : 100ul

Contactez votre distributeur local :

Téléphone : +1 850 650 7790

Marque : Bioss

Contactez votre distributeur local :

Téléphone : +1 850 650 7790

bs-5572R-HRP [Conjugated Primary Antibody]

PIK3R1(Tyr556) Polyclonal Antibody, HRP Conjugated

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DATASHEET

Host: Rabbit

Target Protein: PIK3R1 Tyr556

Modification Site: Tyr556

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5295

Source: KLH conjugated synthetic phosphopeptide derived from human PIK3R1 around the phosphorylation site of Tyr556 [AE(p-Y)RE]

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, 4, 5-triphosphate in response to receptor activation in many signal transduction pathways. Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e.g. p85 alpha). p85 alpha is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane. p85 alpha is necessary for insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.

Conjugation: HRP

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: ELISA(1:500-1000)

Predicted Molecular Weight: 80

Predicted Cross Reactive Species: Human
Mouse
Rat
Dog
Cow
Pig
Horse
Rabbit
Guinea Pig

For research use only. Not intended for diagnostic or therapeutic use.