S6K1 (RPS6KB1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI6B2]
CAT#: TA502929BM
RPS6KB1 (S6K) mouse monoclonal antibody, clone OTI6B2 (formerly 6B2), HRP conjugated
Conjugation: Unconjugated Biotin
Specifications
| Product Data | |
| Clone Name | OTI6B2 |
| Applications | IF, IHC, WB |
| Recommended Dilution | WB 1:500~2000, IHC 1:150, IF 1:100 |
| Reactivities | Human, Dog, Monkey, Mouse, Rat |
| Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human RPS6KB1(NP_003152) produced in HEK293T cell. |
| Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol. |
| Concentration | 0.5 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | HRP |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 59 kDa |
| Gene Name | ribosomal protein S6 kinase B1 |
| Database Link | |
| Background | This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized. [provided by RefSeq] |
| Synonyms | p70 S6KA; p70(S6K)-alpha; p70-alpha; p70-S6K; PS6K; S6K; S6K-beta-1; S6K1; STK14A |
| Reference Data | |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Acute myeloid leukemia, ErbB signaling pathway, Fc gamma R-mediated phagocytosis, Insulin signaling pathway, mTOR signaling pathway, TGF-beta signaling pathway |
Documents
| Product Manuals |
| FAQs |
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| SDS |
Resources
| Antibody Resources |
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Other Versions
| SKU | Description | Size | |
|---|---|---|---|
| CF502929 | Carrier-free (BSA/glycerol-free) RPS6KB1 mouse monoclonal antibody, clone OTI6B2 (formerly 6B2) | 600,00 EUR | |
| TA502929 | RPS6KB1 (S6K) mouse monoclonal antibody, clone OTI6B2 (formerly 6B2) | 447,00 EUR | |
| TA502929AM | RPS6KB1 (S6K) mouse monoclonal antibody, clone OTI6B2 (formerly 6B2), Biotinylated | 509,00 EUR | |
| TA502929S | RPS6KB1 (S6K) mouse monoclonal antibody, clone OTI6B2 (formerly 6B2) | 200,00 EUR |