SLFN11 Antibody
Référence LS-C499826-50
Conditionnement : 50ug
Marque : LSBio
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Téléphone : +1 850 650 7790
Overview
Antibody:
SLFN11 Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IF, WB, ELISA
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
HRP Biotin FITC
Specifications
Description
SLFN11 antibody LS-C499826 is an unconjugated rabbit polyclonal antibody to SLFN11 from human. It is reactive with human and mouse. Validated for ELISA, IF, IHC and WB.
Target
Human SLFN11
Synonyms
SLFN11
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with HRP, Biotin, FITC.
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant human Schlafen family member 11 protein (670-821AA)
Specificity
Interferon (IFN)-induced antiviral protein which acts as an inhibitor of retrovirus protein synthesis. Specifically abrogates the production of retroviruses such as human immunodeficiency virus 1 (HIV-1) by acting as a specific inhibitor of the synthesis of retroviruses encoded proteins in a codon-usage-dependent manner. Binds to tRNAs and exploits the unique viral codon bias towards A/T nucleotides. The exact inhibition mechanism is unclear: may either sequesters tRNAs, prevents their maturation via post-transcriptional processing or accelerates their deacylation. Does not inhibit reverse transcription, integration or production and nuclear export of viral RNA. May play a role in cell cycle arrest and/or induction of apoptosis in response to exogenously induced DNA damage.
Applications
- IHC
- Immunofluorescence
- Western blot
- ELISA
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee About SLFN11
NM_001104587 NP_001098057.1
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