SnoN (SKIL) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2F6]
CAT#: TA800171BM
SKIL mouse monoclonal antibody,clone 2F6, HRP conjugated
Conjugation: Unconjugated Biotin
Specifications
| Product Data | |
| Clone Name | OTI2F6 |
| Applications | IHC, WB |
| Recommended Dilution | WB 1:500~2000, IHC 1:150 |
| Reactivities | Human, Dog, Rat, Monkey, Mouse |
| Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 307-684 of human SKIL (NP_005405) produced in E.coli. |
| Formulation | PBS (pH 7.4) containing 1% BSA, 50% glycerol. |
| Concentration | 0.5 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | HRP |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 76.8 kDa |
| Gene Name | SKI-like proto-oncogene |
| Database Link | |
| Background | The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
| Synonyms | SNO; SnoA; SnoI; SnoN |
| Reference Data | |
| Protein Families | Druggable Genome, Transcription Factors |
Documents
| Product Manuals |
| FAQs |
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| SDS |
Resources
| Antibody Resources |
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Other Versions
| SKU | Description | Size | |
|---|---|---|---|
| CF800171 | Carrier-free (BSA/glycerol-free) SKIL mouse monoclonal antibody, clone OTI2F6 (formerly 2F6) | 600,00 EUR | |
| TA800171 | SKIL (SnoN) mouse monoclonal antibody, clone OTI2F6 (formerly 2F6) | 447,00 EUR | |
| TA800171AM | SKIL mouse monoclonal antibody,clone 2F6, Biotinylated | 509,00 EUR | |
| TA800171S | SKIL (SnoN) mouse monoclonal antibody, clone OTI2F6 (formerly 2F6) | 200,00 EUR |