SOD (Mn) antibody

Référence orb151449-100ug

Conditionnement : 100ug

Marque : Biorbyt

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SOD (Mn) antibody

SOD (Mn) antibody

Catalog Number: orb151449

Catalog Numberorb151449
DescriptionRabbit polyclonal to SOD (PerCP). Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body. It works by catalyzing the dismutation of the superoxide radical O2 to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (2,5). In general, SODs play a major role in antioxidant defense mechanisms. There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge. The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extra-cellular space. SOD3 can also be distinguished by its heparin-binding capacity..
Tested applicationsELISA, ICC, IHC, IP, WB
ReactivityBovine, Canine, Drosophila, Fish, Frog, Gallus, Guinea pig, Hamster, Human, Invertebrate, Monkey, Mouse, Porcine, Rabbit, Rat, Rodent, Sheep
ImmunogenRecombinant Rat Mn SOD Protein
Concentration1 mg/ml
Dilution rangeWB (1:5000), IHC (1:100), ICC/IF (1:120)
UniProt IDP07895
StorageConjugated antibodies should be stored at 4°C
Buffer/PreservativesPBS pH 7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Alternative namesManganese SOD antibody, IPO B antibody, Mn SOD ant
NoteFor research use only
Application notes0.5 µg/ml of SPC-117 was sufficient for detection of Mn SOD in 20 µg of rat brain tissue extract by colorimetric immunoblot analysis using Goat anti-rabbit IgG:AP as the secondary antibody.
Expiration Date12 months from date of receipt.