SSB Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI6G7]

CAT#: TA500427BM

Anti-SSB mouse monoclonal antibody, clone OTI6G7 (formerly 6G7), HRP conjugated

Conjugation: Unconjugated Biotin HRP


Specifications

Product Data
Clone Name OTI6G7
Applications IF, IHC, IP, WB
Recommended Dilution WB 1:1000~2000, IHC 1:150, IF 1:100, IP 2ug/500ul
Reactivities Human, Dog, Monkey
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full-length protein expressed in 293T cell transfected with human SSB expression vector
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation HRP
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 46.8 kDa
Gene Name small RNA binding exonuclease protection factor La
Background La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III (see MIM 606007)-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome (MIM 270150) and systemic lupus erythematosus (SLE; MIM 152700) (Teplova et al., 2006 [PubMed 16387655]).
Synonyms La; La/SSB; LARP3
Reference Data
Protein Families Stem cell - Pluripotency, Transcription Factors
Protein Pathways Systemic lupus erythematosus

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