Cxcr3 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN304051LP

Cxcr3 - mouse gene knockout kit via CRISPR, HDR mediated

Functional Cassette: GFP-puro Luciferase-Puro RFP-BSD mBFP-Neo



HDR-mediated knockout kit validation

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Specifications

Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Donor DNA Luciferase-Puro
Symbol Cxcr3
Locus ID 12766
Components

KN304051G1, Cxcr3 gRNA vector 1 in pCas-Guide CRISPR vector, Target Sequence: GGTATCCGAGCTCGGCCACT

KN304051G2, Cxcr3 gRNA vector 2 in pCas-Guide CRISPR vector, Target Sequence: CGGATACCAGGGACAAGCGT

KN304051LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_009910
UniProt ID O88410
Synonyms Cd183; Cmkar3
Summary This gene encodes a transmembrane protein that functions as a receptor for C-X-R chemokines. Signalling through this protein regulates a variety of biological processes, including inflammation, immunity, and would healing. This protein also plays a role in tumor growth and metastasis. [provided by RefSeq, May 2015]

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