Data Sheet Specifications:
Background
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Description
QuickSwitch™ Tetramer Kit utilizes a patented technique for exchanging up to ten peptides on an MHC class I tetramer. Reduce time and cost with this kit to create your own custom tetramers or to test which peptide sequence has the best peptide-MHC binding affinity. This kit can be used for screening multiple peptides or to create a small amount of your own custom Tetramer in house. The resulting custom tetramers can be used for multiple applications including screening immunogenic peptides, neoantigen discovery, and many other assays downstream from in-silico selection.
FAQs for Peptide Exchange using QuickSwitch™ Kit
| Target: | Custom |
|---|---|
| Product Type: | Tetramer |
| Size: | 1 kit |
| Application: | FCM |
| Research Area / Disease: | Immune Monitoring, Immunology |
| Class: | Class I |
| Allele: | HLA-A*11:01 |
| Peptide Sequence: | Custom |
| Conjugate: | PE |
| Species Reactivity: | Human |
| Specificity: | Custom |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
Citations
Hu, C., Shen, M., Han, X., Chen, Q., Li, L., Chen, S., Jin, A. (2020). Identification of Cross-Reactive CD8 T Cell Receptors with High Functional Avidity to a SARS-CoV-2 Immunodominant Epitope and Its Natural Mutant Variants. Biorxiv. doi:10.1101/2020.11.02.364729